An idea is born, and within months Myra and Nikki have drawn together a group of women who have one thing in common: they have been failed by the American justice system, they're down but they're not out, and they're ready to find their nemeses and make them pay. First up is Kathryn, a long-distance truck driver who was raped at a road stop by three motorcyclists as her paralysed husband watched, helpless. Banding together, the Sisterhood plot the ultimate revenge -- but with dissension from inside the group and out, there's no saying if the plan will work until the moment of truth arrives.